Store at room temperature below 77 degrees F 25 degrees C away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. Laboratory Tests: Therapeutic response to Acarbose Tablets should be monitored by periodic blood glucose tests. Serious and sometimes fatal liver problems have happened with acarbose. Call your doctor right away if you have symptoms of liver problems eg, dark urine, pale stools, persistent loss of appetite, right-sided stomach pain, unusual or severe nausea or tiredness, yellowing of the skin or eyes. Stop eating when you first begin to feel full. tesco brand latisse latisse
Where can I get more information? Acarbose is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels. Hypoglycemia: Because of their mechanism of action, Acarbose Tablets when administered alone should not cause hypoglycemia in the fasted or postprandial state. Sulfonylurea agents or insulin may cause hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose, it may increase the potential for hypoglycemia. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. Oral glucose dextrose whose absorption is not inhibited by Acarbose Tablets, should be used instead of sucrose cane sugar in the treatment of mild to moderate hypoglycemia. Sucrose, whose hydrolysis to glucose and fructose is inhibited by Acarbose Tablets, is unsuitable for the rapid correction of hypoglycemia. cefadroxil
Hyperglycemia high blood sugar may occur if you do not take enough or skip a dose of your antidiabetic medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual. Also avoid dairy products and alcohol. And avoid eating solids and drinking liquids during the same meal. In fact, don't drink 30 minutes before and 30 minutes after meals. Your doctor may want you to stop taking acarbose for a short time if you become ill, have a fever or infection, or if you have surgery or a medical emergency. This medication should not be used if you have certain medical conditions.
Discuss the risks and benefits with your doctor. This list is not complete and other drugs may affect your blood sugar or interact with acarbose. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Fertility studies conducted in rats after oral administration produced no untoward effect on fertility or on the overall capability to reproduce. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. prescription buspar
It is a group of symptoms that may result from having part of your removed or from other surgery involving the stomach. The symptoms range from mild to severe and often subside with time. Although you may find dumping syndrome alarming at first, it is not life threatening. You can control it by making changes in what and how you eat. Eight carcinogenicity studies were conducted with Acarbose. Six studies were performed in rats two strains, Sprague-Dawley and Wistar and two studies were performed in hamsters. Acarbose Tablets as monotherapy or in combination with sulfonylurea, metformin or insulin treatment was conducted in Canada in which 316 patients were included in the primary efficacy analysis Figure 2. In the diet, sulfonylurea and metformin groups, the mean decrease in HbA1c produced by the addition of Acarbose Tablets was statistically significant at six months, and this effect was persistent at one year. In the Acarbose Tablets-treated patients on insulin, there was a statistically significant reduction in HbA1c at six months, and a trend for a reduction at one year. Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. After gastric surgery, it can be more difficult to regulate movement of food, which dumps too quickly into the small intestine. Eating certain foods makes dumping syndrome more likely. For example, refined sugars rapidly absorb water from the body, causing symptoms. Symptoms may also happen after eating dairy products and certain fats or fried foods. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency. It is not known whether acarbose passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using acarbose. Choose from Top Nursing Uniform Companies. All sizes, styles and popular name brands available. Abteilung Klinische Pharmakologie, Universitat Gottingen, Gottingen, Germany. A1c, complete blood counts should be performed periodically to check for side effects and monitor your response to therapy. Check your blood or urine sugar levels regularly as directed by your doctor or pharmacist. To evaluate the long-term efficacy of precose in improving glycemic control in subjects with NIDDM, a one-year, multicenter, randomized, double-blind, placebo-controlled study was conducted. The study involved 354 subjects with NIDDM. Clinical studies demonstrated a strong association between hyperglycemia and an increased risk of microvascular tissue damage. Trials involving Precose established that hemoglobin levels are a more significant predictor of the onset or progression of retinopathy in NIDDM diabetic patients than blood glucose concentration. Precose significantly reduced hemoglobin levels in NIDDM subjects maintained on dietary therapy alone. The magnitude of the treatment effect steadily increased during active treatment; diabetic retinopathy was reduced by approximately 30%. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly. Acarbose. In rabbits, reduced maternal body weight gain, probably the result of the pharmacodynamic activity of high doses of Acarbose in the intestines, may have been responsible for a slight increase in the number of embryonic losses. The dosage is based on your medical condition, weight, and response to therapy. Your dose may be gradually increased to determine the most effective dose for you. The manufacturer recommends that you do not take more than 300 milligrams per day. I'm already on ALA and when my bottle runs out next week yes, will be one of the first people trying out the r-ala.
In a study of 6 healthy men, less than 2% of an oral dose of Acarbose was absorbed as active drug, while approximately 35% of total radioactivity from a 14C-labeled oral dose was absorbed. An average of 51% of an oral dose was excreted in the feces as unabsorbed drug-related radioactivity within 96 hours of ingestion. Because Acarbose acts locally within the gastrointestinal tract, this low systemic bioavailability of parent compound is therapeutically desired. Following oral dosing of healthy volunteers with 14C-labeled Acarbose, peak plasma concentrations of radioactivity were attained 14-24 hours after dosing, while peak plasma concentrations of active drug were attained at approximately 1 hour. The delayed absorption of Acarbose-related radioactivity reflects the absorption of metabolites that may be formed by either intestinal bacteria or intestinal enzymatic hydrolysis. Renal Impairment: Plasma concentrations of Acarbose Tablets in renally impaired volunteers were proportionally increased relative to the degree of renal dysfunction. If you miss a dose, take the next dose with your next meal or snack as directed. If you take acarbose with insulin or other diabetes medications, your blood sugar could get too low. Low blood sugar hypoglycemia can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating. People with diabetes must take acarbose with the first bite of food at each meal. Acarbose may be used alone as the only diabetes medicine, or with the group of blood-sugar-lowering medicines called sulfonylureas, such as the brand names Diabeta, Glucotrol, and Micronase. Take exactly as prescribed by your Health Provider. The presence of other medical problems may affect the use of acarbose. Precose slows the digestion of carbohydrate sugars and starches in the small intestine. bonviva
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Precose therapy or placebo, titrating to a maximum dose of 100 mg three times daily. In case of overdose, do not eat or drink anything containing carbohydrates for the next 4 to 6 hours. What should I avoid while taking acarbose? Precose decreases peaks in blood glucose levels that occur after eating by delaying absorption of carbohydrates sugar and starches into the bloodstream. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Always consult your doctor or healthcare specialist for medical advice. Especially since I cannot stand seafood. Acarbose may also be used for purposes not listed in this medication guide. Carefully follow the regular testing of urine or blood glucose schedules given to you by your health care provider.
Drink liquids 30 to 45 minutes after meals. Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Macrovascular Outcomes: There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with Acarbose Tablets or any other anti-diabetic drug. Overdose symptoms may include bloating, gas, or stomach discomfort. Because its mechanism of action is different, the effect of Acarbose Tablets to enhance glycemic control is additive to that of sulfonylureas, insulin or metformin when used in combination. In addition, Acarbose Tablets diminish the insulinotropic and weight-increasing effects of sulfonylureas. If you have not already been diagnosed with the dumping syndrome, and you have confusion, dizziness, rapid heartbeat, or fainting, get immediate medical help. Call 911 right away. Lack of interaction between thioctic acid, glibenclamide and acarbose. Nursing Mothers: A small amount of radioactivity has been found in the milk of lactating rats after administration of radiolabeled Acarbose. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, Acarbose Tablets should not be administered to a nursing woman. Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region. The Drugs. The beans are all very fibrous, complex carbs and release the sugars very slowly - stick to the ribs as they say. Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition. Consult your doctor because this may require a change in your treatment plan, medications, or blood sugar testing. Swallow the food or liquid right away, making sure not to chew the medication. Drink a glass of water or juice after swallowing the food to make sure all the medication is swallowed. Do not save the medication mixture for later. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. where to buy tacrolimus in us
Acarbose Tablets were statistically significantly different from placebo at all doses with respect to effect on one-hour postprandial plasma glucose. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Nursefriendly, Inc. or any of it's affiliated companies. Information for Patients: Patients should be told to take Acarbose Tablets orally three times a day at the start with the first bite of each main meal. Mostly you will be prescribed one 500mg Glycomet Generic Glucomin tablet 3 times a day, while the 850mg tablets are usually taken twice daily to give effective diabetes control. You should use Glycomet Generic Glucomin only as directed by your doctor. Your pharmacist can provide more information about acarbose. It is not known whether this drug passes into milk. Consult your doctor before -feeding. Do not change brands or dosage forms of without consulting your doctor or pharmacist. United States and its territories. Indications, uses and warnings on Drugs. Acarbose does not usually cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal, exercise heavily, or drink alcohol. It may also be more likely if you take acarbose along with certain medicines for diabetes eg, sulfonylureas, insulin. Tell your doctor right away if you experience symptoms of low blood sugar eg, fast heartbeat, headache, chills, sweating, tremors, increased hunger, vision changes, nervousness, weakness, dizziness, drowsiness, fainting. It is a good idea to carry a reliable source of glucose eg, tablets or gel to treat low blood sugar. This will raise your blood sugar level quickly. Because acarbose prevents the breakdown of table cane sugar, be sure to use glucose dextrose not sugar or fruits, to treat symptoms of low blood sugar. Contact your health care provider if you have any questions. Acarbose has no inhibitory activity against lactase and consequently would not be expected to induce lactose intolerance. Eat five or six small meals or snacks a day. What should I avoid while taking acarbose Precose? Acarbose treatment resulted in a significant increase in the incidence of renal tumors adenomas and adenocarcinomas and benign Leydig cell tumors. This study was repeated with a similar outcome. Further studies were performed to separate direct carcinogenic effects of Acarbose from indirect effects resulting from the carbohydrate malnutrition induced by the large doses of Acarbose employed in the studies. In one study using Sprague-Dawley rats, Acarbose was mixed with feed but carbohydrate deprivation was prevented by the addition of glucose to the diet. In a 26-month study of Sprague-Dawley rats, Acarbose was administered by daily postprandial gavage so as to avoid the pharmacologic effects of the drug. In both of these studies, the increased incidence of renal tumors found in the original studies did not occur. Acarbose was also given in food and by postprandial gavage in two separate studies in Wistar rats. No increased incidence of renal tumors was found in either of these Wistar rat studies. In two feeding studies of hamsters, with and without glucose supplementation, there was also no evidence of carcinogenicity.
If the prescribed diet is not observed, the intestinal side effects may be intensified. If strongly distressing symptoms develop in spite of adherence to the diabetic diet prescribed, the doctor must be consulted and the dose temporarily or permanently reduced. The way in which these drugs work is also the major source of their side effects. Although these drugs are very safe, their side effects can be annoying. If digestion is greatly inhibited, this may cause abdominal bloating, gas and diarrhea. The alpha glucosidase inhibitors should always be started on a minimal dose, often half of the smallest tablet, and then gradually increased over time. This greatly minimizes gastric side effects; side effects also tend to decrease over time. At first the dose is 25 milligrams mg three times a day, at the start of each main meal. Your dose may then be adjusted by your doctor. The dose of acarbose will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of acarbose. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. What other drugs will affect acarbose? In contrast to sulfonylureas, Acarbose Tablets do not enhance insulin secretion. The antihyperglycemic action of Acarbose results from a competitive, reversible inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucoside hydrolase enzymes. Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine, while the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the brush border of the small intestine. In diabetic patients, this enzyme inhibition results in a delayed glucose absorption and a lowering of postprandial hyperglycemia. During treatment initiation and dose titration see below one-hour postprandial plasma glucose may be used to determine the therapeutic response to Acarbose Tablets and identify the minimum effective dose for the patient. Thereafter, glycosylated hemoglobin should be measured at intervals of approximately three months. The therapeutic goal should be to decrease both postprandial plasma glucose and glycosylated hemoglobin levels to normal or near normal by using the lowest effective dose of Acarbose Tablets, either as monotherapy or in combination with sulfonylureas, insulin or metformin. Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection. Be sure your family and close friends know how to help you in an emergency. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Geriatric Use: Of the total number of subjects in clinical studies of Acarbose Tablets in the United States, 27% were 65 and over, while 4% were 75 and over. No overall differences in safety and effectiveness were observed between these subjects and younger subjects. Take this medication by with meals and snacks as directed by your doctor. Swallow the capsule whole. where to danocrine in singapore
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Do NOT take more than the recommended dose without checking with your doctor. Other Abnormal Laboratory Findings: Small reductions in hematocrit occurred more often in Acarbose Tablets-treated patients than in placebo-treated patients but were not associated with reductions in hemoglobin. Low serum calcium and low plasma vitamin B 6 levels were associated with Acarbose Tablets therapy but are thought to be either spurious or of no clinical significance. Diarrhea, gas, upset stomach, constipation, or stomach pain may occur in the first few weeks of treatment as your body adjusts to this medication but usually improve with time. Follow your prescribed diet to help lessen these side effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. buy generic coversyl in usa coversyl
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Symptoms of an early phase happen because food is rapidly "dumping" into the small intestine. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages because they can increase the risk of developing low blood sugar.
What should I discuss with my healthcare provider before taking acarbose Precose? If any of these effects persist or worsen, tell your doctor or promptly. Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. isaca.info amlodipine
There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification ID bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines. If your symptoms do not improve or if they become worse, check with your doctor. The native american diet is largely unchanged, except where Western influence has taken over - hence high rates of obesity, diabetes, and alcoholism - they are all interrelated. Now, understand that I am of Western European descent, so I do NOT consider myself an expert on native american diets.